The ACIP recommends PCV13 for all children 2 through 59 months of age and for children 60 through 71 months of age who have underlying medical conditions that increase their risk of pneumococcal disease or complications.

　　1. Infants and children who have not previously received PCV7 or PCV13

　　o The ACIP recommendation for use of PCV13 and the immunization schedules for infants and toddlers 2 through 59 months of age who have not received any prior PCV7 or PCV13 doses are the same as those previously published for PCV7 with PCV13 replacing PCV7 for all doses (MMWR 2000; 49 (RR-9).

　　Infants 2 through 6 months of age

　　o PCV13 is recommended as a 4-dose series at 2, 4, 6, and 12 through 15 months. Infants receiving their first dose at age <6 months should receive 3 doses of PCV13 at intervals of approximately 8 weeks (the minimum interval is 4 weeks). Minimum age for administration of first dose is 6 weeks. The fourth dose is recommended at age 12 through 15 months and should be given at least 8 weeks after the third dose (Table 1).